by Rebecca Foxton
You need to be careful when choosing which heartworm prevention medication that you give your dog, given the seriousness of a heartworm infestation.
Proheart Six, first available in 2001, is a medication administered as one injection once every six months. This was originally seen as a safe & simple way to provide heartworm prevention every six months. However it peaked the FDA’s attention after more than 5,000 reports were filed detailing poor reactions, which included 415 deaths.
The FDA investigated and figures show the number of deaths per year caused by adverse reactions to ProHeart 6 were much higher than monthly heartworm medications. On average of 138 deaths a year compared with as few as 6 for Heartgard heartworm protection and Sentinel. (Source FDA: As of 05/03/2004)
While our intentions are not to scare pet owners away from necessary treatment, we feel that they should know that allergic reactions can result from heartworm control. It is possible that death could be the result of the medication. Obviously this is the worst-case scenario.
According to the FDA (2004), Revolution heartworm protection had reports of an average of 36 annual deaths from over 8,500 reactions. Keep in mind however, that the statistics read higher than Proheart 6, simply because the product has been on the market much longer and has been administered to many more pets. Proheart 6 has actually caused more than three times as many deaths.
Revolution is not necessarily unsafe. The high numbers of deaths are partially due to its very widespread use, however you should still educate yourself on the facts. Only 214 negative reactions were caused by Interceptor for canines, which is eight times less than Revolution. Interceptor averages a mere nine deaths per year, compared to ProHeart Six’s average of 138.
Indeed between 1995 and 2004 only 84 deaths were recorded for Interceptor heart worm protection. Heartgard, which uses ivermectin for heartworm protection in its Heartgard chewables, had an average of 355 reactions and 6 deaths.
Causing the very least amount of allergic reactions or deaths was Sentinel, a flea, parasite and heartworm protection medication. Statistics show that information gathered in the years of 1999 through 2004 that Sentinel heartworm prevention for dogs resulted in 900 reactions which is an average of 233 as opposed to Revolution heartworm treatment for dogs which had 1,737 reactions with a total of 25 deaths averaging to be 6 annually.
Proheart 6 is not recommended for established heartworm infections, but only preventative heartworm control for dogs. Many vets still believe Proheart to be safe if properly prepared and administered, but many choose monthly heart worm prevention and treatment as a safer option. Proheart 6 was recalled in September 2004 but is still available in 2007 as a heartworm protection medicine.
Keep in mind that these statistics are resulted from millions of dogs that have received medications from all over the world. Since your pet is a member of the family and not a statistic on paper, you should speak with the family vet so that he can aid you in choosing the right form of preventative.
Please do not underestimate the devastating effect of heartworms in dogs. By choosing an easy to administer monthly dose of heartworm preventive medicine, you can spare your pet a lot of hardship.
About the Author:
Author Rebecca Foxton wants to help you bring your pet better health with
Interceptor For Dogs. Check out her nutrition tips for pet owners, and read her
Fortiflora article series on Dog Buffs.